Li Leijie 李磊杰Ph.D
Bioinformatics, School of Life Sciences and Biotechnology |
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Education [CV]
| 2011.09-2015.06 | Northwest A&F University | Biotechnology (Bachelor) |
CLASS: Bioinformatics, Perl Language, Biostatistics, Genomics and Proteomics, Full Research Training, Genetic Engineering
GPA: 84.6/100 (3.22/4.00); Passed CET6
GPA: 84.6/100 (3.22/4.00); Passed CET6
| 2015.09-2018.06 | Northwest A&F University | Bioinformatics (Master) |
CLASS: Advanced bioinformatics, Modern statistical model and algorithm, Machine Learning, Data Mining, Scientific Paper Writing
GPA: 80/100;
GPA: 80/100;
| 2018.07-now | Shanghai Jiao Tong Univercity | Bioinformatics (Ph.D.) |
Research Interests
- Machine learning and feature engineering for biological network, such as Protein-Protein Interaction Network (PPIN).
- Identification query genes in tumors or stem cells by analyzing high-throughout sequencing data.
Research Experience
Bachelor:
- Completed the College Student’s independent Experiment: “Milk Capra ETV5 Genes Clone and Primarily Analysis” under the guidance of Dr. Hua Jinlian in College of Animal Medical Northwest A&F University.
- Completed the College Student’s Scientific Innovation project:” Functions of Three "core" pluripotency transcription factors in Human Embryonic Stem Cells” under the guidance of Dr. Liao Mingzhi. And the work was assessed as the excellent project by the school authority.
- Engaged in Genetic Engineering Project, and learnt the basic experimental principles in molecule lab.
Master:
- Maintaining a Small-Scale Server (system: CentOS 6.5).
- Processing spermatogonia stem cell RNA-seq data for a wet lab student.
- Topological attribute analysis of hub protein in Protein-Protein interaction network (PPIN).
- Identified the targets of the Transcription Factors (OCT4, SOX2 and NANOG) in human stem cells by machining learning algorithm for instance Support Vector Machine (SVM), random forest.
- Using python designed and coded a software aiming to identify human cell type and made a simple website, named CellSim, which is not released. [website] [code]
Activities
Academic:
- 2014.10 The Second national Developmental biology conference.
- 2015.07 The “Dragon Star” Bioinformatics Summer Classes -“The application of Bioinformatics in Precision Cancer Medicine”.
- 2015.07 The 12th International Bioinformatics Workshop, IBW2015.
Social Service:
- 2012.07 Finished a report of “Cooperative Medical System and Pension in Chinese Rural Area” by surveying the villagers in Hebei province
- 2013.09 Offered help to local elderly people without children.
- 2014.03 Volunteered for local government
Honors and Awards
- 2014.10 Won the first price of academic paper at Northwest A&F University.
- 2014.12 Won the first price in the First Poster Design and Display competition at You Ren Academy.
- 2015.03 Won the first price in the Third Undergraduate Innovation and Entrepreneurship Forum at Northwest A&F University.
- 2015.05 Won the first price in the Tenth Challenge-cup Extracurricular and Academic Contest at Shaanxi province.
- 2015.06 Gained the title of “the Excellent Graduation Thesis” at Northwest A&F University.
- 2015.06 Gained the title of “the Outstanding Graduates” at College of Life Sciences.
- 2011-2014 Won the Professional scholarship three times. (2011-2014).
- 2015.12 Won the Master National Scholarship.
Publications
- Leijie Li, Liangcai Zhang, Guiyou Liu, Rennan Feng, Yongshuai Jiang, Lei Yang, Shihua Zhang, Mingzhi Liao, and Jinlian Hua. "Synergistic transcriptional and post-transcriptional regulation of ESC characteristics by core pluripotency transcription factors in protein-protein interaction networks." PloS one 9, no. 8 (2014): e105180. [paper]
- Leijie Li, Zhaobin Chen, Liangcai Zhang, Guiyou Liu, Jinlian Hua, Lianghui Jia, and Mingzhi Liao. "Genome-wide targets identification of “core” pluripotency transcription factors with integrated features in human embryonic stem cells." Molecular BioSystems 12, no. 4 (2016): 1324-1332. [paper]